Cell Lines and Cell Cultures
![Biolegend PE/Fire™ 640 anti-human CD305 (LAIR1) [NKTA255]; Isotype: Mouse IgG1; Reactivity: Human; Apps: FC; Size: 25 tests](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Biolegend PE/Fire™ 640 anti-human CD305 (LAIR1) [NKTA255]; Isotype: Mouse IgG1; Reactivity: Human; Apps: FC; Size: 25 tests
PE/Fire™ 640 anti-human CD305 (LAIR1) [NKTA255]; Isotype: Mouse IgG1; Reactivity: Human; Apps: FC; Size: 25 tests
Human respiratory syncytial virus strain A2 (ATCC VR-1540™)
Human respiratory syncytial virus strain A2 (ATCC VR-1540™) is a whole-genome sequenced virus isolated from the lower respiratory tract of an infant with bronchiolitis and bronchopneumonia in Melbourne, Australia. Used in respiratory disease research and molecular assay development. Recommended companion products: Genomic RNA (Fisher Cat. No. 50-238-2423, ATCC VR-1540DQ™), HEp-2 cells (Fisher Cat. No. 50-238-5019, ATCC CCL-23™), EMEM (Fisher Cat. No. 50-238-2632, ATCC 30-2003™), and Fetal bovine serum (Fisher Cat. No. 50-238-3771, ATCC 30-2020™).
ATCC 10 strain mix; whole cell material
NGS Standards are mock microbial communities that mimic mixed metagenomic samples. This product is prepared as a mixture of whole cells and comprises fully sequenced, characterized, and authenticated ATCC Genuine Cultures that were selected based on relevant phenotypic and genotypic attributes, such as Gram stain, GC content, genome size, and spore formation. Each order for this product is provided with access to run 5 analyses on One Codex, the leading bioinformatics platform for microbial genomics and metagenomics. Specification Range: 2x107 cells/vial ± 1 log* *Whole cell concentrations indicate ATCC manufacturing specifications and are provided as a reference only
Biochain Institute Inc Paraffin Tissue Section - Human Bladder Tumor: Papillary Transitional Cell Carcinoma, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Biochain Institute Inc Paraffin Tissue Section - Human Tumor Cell Line: MCF-7, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. The cultured tumor cells were harvested, fixed, and embedded in paraffin using proprietary method. The paraffin embedded cell pellet was then sectioned and mounted on positively charged slides. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Eurofins Discoverx PathHunter CHO-K1 OXER1 β-Arrestin Cell Line, 2 vials. (93-0867C2)
The PathHunter OXER1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. 5-oxo-ETE) based activation of OXER1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OXER1 and EA-tagged β-Arrestin-2. Activation of OXER1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CCR4 Total Internalization U2OS Cell Line, 2 vials. (93-0845C3)
The PathHunter CCR4 Total Internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of CCR4 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged CCR4 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the CCR4 receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter U2OS IL2RB/IL2RG Dimerization Cell Line, 2 vials. (93-0998C3)
The PathHunter IL2RB/IL2RG Dimerization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This cell line enables assessment of ligand (e.g. IL-2) induced dimerization of IL2RB/IL2RG receptors. This product uses EFC technology. The cell line included overexpresses IL2RB target protein fused to PK alongside IL2RG target protein fused to EA. Upon ligand-induced dimerization of IL2RB/IL2RG, detectable EFC signal is produced. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/interleukins.
Eurofins Discoverx PathHunter U2OS KISS1R β-Arrestin Cell Line, 2 vials. (93-0927C3)
The PathHunter KISS1R cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. kisspeptin) based activation of KISS1R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged KISS1R and EA-tagged β-Arrestin-2. Activation of KISS1R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 rCNR2 (CB2) β-Arrestin Cell Line, 2 vials. (93-0922C2)
The PathHunter rCNR2 (CB2) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand-induced based activation of rCNR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rCNR2 and EA-tagged β-Arrestin-2. Activation of rCNR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter U2OS FLT3 Activity Assay, 2 vials. (93-0901C3)
The PathHunter FLT3 RTK Activity cell line is a stable, engineered cell line for use in studying small molecule drug candidates targeting RTKs. This cell line enables assessment of RTK activity via detection of resulting FLT3 phosphorylation-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged FLT3 to the extracellular ligand binding domain of EGFR alongside an EA-tagged SH2 domain protein. Upon ligand induced receptor activation, cross-phosphorylation of the receptor leads to SH2-EA recruitment and production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Brain: Postcentral Gyrus, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx CHO-K1 PTAFR Gq Cell Line, 2 vials. (95-0091C2)
The PTAFR Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. PAF) based activation of PTAFR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses PTAFR, a naturally Gq coupled GPCR. Upon activation of PTAFR, the resulting calcium activity can be fluorescently assayed using the Calcium No WashPLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 DRD1 β-Arrestin Cell Line, 2 vials. (93-0590C2)
The PathHunter DRD1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine) based activation of DRD1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged DRD1 and EA-tagged β-Arrestin-2. Activation of DRD1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Genscript Corporation CHO-K1/GLP2R/G15 Stable Cell
The glucagon-like peptides include glucagon GLP-1 and GLP-2 exert diverse actions on nutrient intake gastrointestinal motility islet hormone secretion cell proliferation and apoptosis as well as nutrient absorptionand assimilation Glucagon-like peptide (GLP)-2 a product of the proglucagon gene is expressed in enteroendocrine cells of the small and large intestine and is trophic to the gastrointestinal mucosa GLP-2 also inhibits gastric acid secretion and emptying and up-regulates intestinal hexose transport GLP-2 acts via binding to a single G protein-coupled GLP-2 receptor (GLP-2R)